Epidemiology, virology, clinical features, diagnosis, and treatment of SARS-CoV-2 infection

نویسندگان

چکیده

Since December 2019, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has emerged and spread quickly worldwide. The disease is generally mild in adult people but any with comorbidities may proceed to distress (ARDS), pneumonia, multi-organ dysfunction. By performing molecular tests on secretions can diagnose virus. Elevated C-reactive protein (CRP) normal/low white cell counts are common laboratory diagnoses of COVID-19 while tomographic chest scan usually irregular for many infected people. Some patients progress failure, finally death by end first week illness because sharp rise inflammatory cytokines such as IL7, IL2, GCSF, IL10, MIP1A, MCP1, IP10, TNF?. Various approaches COVID- 19 being performed scientists. Use chemical medical drugs that effective other viral infections. Among them, remdesivir was approved FDA 1th May 2020 its impact treat patients. Also, several studies have revealed Chinese herbal remedies a remarkable healing process when simultaneously were used along pharmacological drugs. In meantime, efforts been made produce an vaccine, so far, Ad5-vectored vaccine successful entered phase human trial. current review focus epidemiology, virology, clinical features, diagnosis, available treatment might assist researchers clinicians establishing action options timely against this infection.

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ژورنال

عنوان ژورنال: Journal of experimental and clinical medicine

سال: 2021

ISSN: ['1309-5129', '1309-4483']

DOI: https://doi.org/10.52142/omujecm.38.4.44